Smoking ups risk of
developing second cancer
A large study has found that cigarette smoking prior to
the first diagnosis of lung (stage I), bladder, kidney or head and neck cancer
increases the risk of developing a second smoking-associated cancer.
"As survival improves for a number of
smoking-related cancers, patients are living longer; however, smoking may
increase the risk of developing a second smoking-related cancer among these
survivors," said Meredith S. Shiels, lead study author and research fellow
with the National Cancer Institute's Division of Cancer Epidemiology and
Genetics.
Researchers examined data from five cohorts which
included 2,552 patients with stage I lung, 6,386 with bladder, 3,179 with
kidney and 2,967 with head and neck cancer.
They found that the association between smoking and
developing a second primary smoking-associated cancer was similar to the
association between smoking and developing a first primary smoking-associated
cancer.
Patients who smoked more than 20 cigarettes per day had
a 5.41-fold higher risk of developing cancer than individuals who have never
smoked.
Notably, current smoking at any level increased the
risk of overall mortality across all cancer disease sites.
"Our study demonstrates that health care providers
should emphasise the importance of smoking cessation to all their patients,
including cancer survivors," Shiels concluded.
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